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绝经前女性尿钙尿肌酐比值正常范围确立及临床应用研究

Establishing normal range of urinary calcium/creatinine ratio with its clinical application in premenopausal women
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摘要 目的:初步确立绝经前成年女性尿钙尿肌酐比值(Ca/Cr)正常参考范围,并探讨其临床上的应用价值。方法:随机选择无影响钙、肌酐代谢疾患因素的绝经前成年女性体检者110例,收集空腹晨尿并检测尿钙尿肌酐,计算其比值。经过分析确立其正常范围。作尿钙尿肌酐比值排列图、观察尿钙尿肌酐比值与年龄的分布情况。结果:各年龄组的空腹尿钙、尿肌酐、尿钙尿肌酐比值均无显著差异(P〉0.05)。尿钙尿肌酐比值(Ca/Cr)呈偏态分布,计算得出正常参考范围为0.033(mmol/L/mmol/L)~0.586(mmol/L/mmol/L)。结论:本实验确定了本地区尿钙尿肌酐比值的正常参考范围,为其他实验室确定尿钙尿肌酐比值参考范围提供参考。 Objective: To establish normal reference range of urinary calcium/creatinine ratio ( U - Ca/Cr) in the adult female and study the U - Ca/Cr ratio value of clinical application. Methods : We have randomly selected 110 premenopausal adult women without any factors of affecting calcium and creatinine metabolism, and collected their fasting urina sanguinis. The urinary calcium and creatinine levels with their ratios were measured. The U - Ca/Cr ratios data were made into the map and observed their correlation with different age groups. Results.The urinary calcium and creatinine levels with their ratios in the different age groups were statistically similar ( P 〉 0. 05 ). The skewness distribution were showed in the U - Ca/Cr ratios data. The normal range of the U - Ca/Cr ratios was 0. 033 (mmol/L/mmol/L) - 0. 586 (mmol/L/mmol/L). Conclusion: The fasting U - Ca/Cr ratio is convenient in the clinical use because its fluctuation about dietary factor is tiny. The study has established the U - Ca/Cr ratio normal reference range in Quzhou area, and also provided the information for other lab.
出处 《中国卫生检验杂志》 CAS 2009年第7期1583-1584,共2页 Chinese Journal of Health Laboratory Technology
基金 国家民政部十一五期间老年学会研究科研立项项目课题:民人教科字(2007)18-1-33
关键词 正常参考范围 尿钙 尿钙尿肌酐比值 Normal reference range Urinary calcium Urinary calciuin/creatinine ratio
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