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甲亢舒配合^(131)碘治疗甲状腺功能亢进症临床应用研究

Clinical study on the therapeutic effect of combined 131I and "Jia kang shu"on hyperthyroidism
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摘要 我院于1993年12月至1997年10月用131碘治疗甲状腺机能亢进症(简称甲亢)病人5040例中,应用“甲亢舒”配合131碘治疗(简称治疗组)4265例;单用131碘治疗(简称对照组)775例。在应用131碘治疗的“空白区”期间对病人病情进行系统观察,结果表明:1.症状加重治疗组为2.23%,对照组为92.39%(P<0.01);2.甲亢危象发生率治疗组为0%,对照组为2.45%(P<0.01);3.治疗4周时甲亢症状改善治疗组明显优于对照组(P<0.01);4.血清FT3、FT4浓度变化:治疗组明显下降,对照组虽有下降,但下降的速度也不如治疗组(P<0.05)。5.甲亢舒能明显提高131碘疗效。表明“甲亢舒”配合131碘治疗甲亢,能迅速缓解临床症状,降低血清FT3、FT4浓度;减少131碘治疗的并发症;增加131碘的治疗效果。 Between December 1993 and October 1997,5040 cases with hyperthyroidism were treated with131I in our hospital,and 4265 of the above-mentioned patients were treated with combined 131I and Jia kang shu(treated group),the other 775 cases were treated only with 131I(contrast group)The clinical result showed that:(1)Symptom exacerbation in treated group was 223%,and 9239%(P<001)in contrast group;(2)Crisis incidence of hyperthyroidism was 0% in treated group,and 245%(P<001)in contrast group;(3)Symptom improvement during 4th week treatment in treated group was obviously better than that in contrast group (P<001);(4)A marked drop of the concentration of serus FT 3、FT 4 happened in treated group,and there was only a little in contrast group(P<005);(5)Jia kang shu could markedly improve the therapeutic effect of 131I Based on these findings,we concluded that the effect of treatment combined 131I and Jia kang shu in hyperthyriodism was better than that of only with 131I,it could relief the clinical symptom,lower concentration of serus FT 3、FT 4,reduce the complication and reinforce the effect of 131I \ \
出处 《广西医学》 CAS 1998年第4期534-537,共4页 Guangxi Medical Journal
关键词 甲状腺机能亢进 碘131 药物疗法 甲亢舒 Hyperthyroidism \ Jia kang shu 131I
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