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丙型肝炎的免疫学研究热点 被引量:1

Hot issues of immunology in viral hepatitis C
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摘要 目前,长效α干扰素和利巴韦林联合应用作为丙型肝炎治疗的“标准方案”,其持久病毒学应答率只有50%,而且不良反应大,费用昂贵,停止治疗后仍有很高的复发率^[1]。由于HCV的基因组变异率高,缺乏有效的细胞和小动物感染模型,对其细胞免疫和体液免疫在HCV感染恢复中的作用认识仍然不是十分清楚,使得以诱导保护性抗体产生为目的的预防性疫苗和(或)治疗性疫苗的研究也步履艰难^[2]。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2009年第7期490-493,共4页 Chinese Journal of Hepatology
关键词 肝炎病毒 丙型 肝炎 丙型 免疫学 Hepatitis C virus Hepatitis C Immunology
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参考文献26

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