摘要
目的评价两种方案治疗慢性丙型肝炎的经济效果。方法将75例慢性丙型肝炎患者按治疗方案分为α干扰素(IFN-α-2a)组和聚乙二醇-干扰素(PEG-IFN-α-2a)组,观察两组的疗效并运用药物经济学方法进行成本-效果分析。结果 IFN-α-2a组疗效与PEG-IFN-α-2a组比较,差异有统计学意义(P<0.05),但成本-效果比较低。结论治疗慢性丙型肝炎,IFN-α-2a组较PEG-IFN-α-2a组更经济,可在临床推广应用。
Objective To evaluate the economic effects of two therapeutic schemes for chronic hepatitis C.Methods 75 patients with chronic hepatitis C were divided into 2 groups,the group IFN-α-2a and the group PEG-IFN-α-2a.The therapeutic efficacy was observed and cost-effectiveness analysis was performed in the two groups.Results There was significant difference in the clinical efficacy between the group IFN-α-2a and the group PEG-IFN-α-2a,and the cost-effectiveness ratio in the group IFN-α-2a was lower than that in the PEG-IFN-α-2a.Conclusion The IFN-α-2a scheme is more economical for treating chronic hepatitis C than the PEG-IFN-α-2a scheme and deserves to be popularized.
出处
《现代医药卫生》
2012年第21期3240-3241,3245,共3页
Journal of Modern Medicine & Health
关键词
干扰素类
前列腺素
慢性病
肝炎
丙型
费用效益分析
Interferons
Prostaglandins
Chronic disease
Hepatitis C
Cost-benefit analysis