摘要
用２．２．１５细胞系模型，连续１３ｄ检测ＨＢｓＡｇ、ＨＢｅＡｇ、ＨＢＶ－ＤＮＡ，动态观察肝康对其的抑制作用。结果：①均有一个相似的药物作用曲线，即从用药到见效需３～４ｄ，较强的抑制可维持３～５ｄ，然后逐渐减弱、消失；②分泌、复制越是旺盛，抑制作用越强；
We used Transfection Cells (HepG2 2.2.15 cells) to observe the inhibiting action of Gankang by detecting HBsAg, HBeAg and HBV DNA once a day for 13 days. Results: a) There was a similar inhibiting action curve on HBsAg and HBeAg secretion and HBV DNA replication, which showed it needed 3～4 days to introduce the action, the strong action would maintain 3～5 days, then it decreased to disappear gradually. b) The more active HBV replicated, The stronger Gankang inhibiting action was. c) The relationship of drug quantity and its effects was positive correlation.
出处
《中国实验方剂学杂志》
CAS
1998年第4期18-22,共5页
Chinese Journal of Experimental Traditional Medical Formulae
基金
广东省中医药管理局资助
