摘要
目的了解江苏省吸毒者美沙酮维持治疗(MMT)保持时间及其影响因素。方法在江苏省美沙酮社区药物维持治疗门诊点,调查参加维持治疗的吸毒者的社会人口学和吸毒行为,用生存分析方法分析维持治疗时间及其影响因素。结果2006年美沙酮维持治疗的1358名吸毒者维持治疗时间中位数为603d,590人退出治疗;吸毒者1年和2年的维持概率分别为72.81%和52.76%。多因素Cox比例风险回归模型分析,性别、婚姻状况、首次吸毒年龄和美沙酮维持剂量对美沙酮维持治疗保持时间有显著影响。结论江苏省吸毒者MMT的保持率较高,但在24个月后维持率出现快速的下降。需要加强对吸毒人群的心理辅导和社会帮扶工作,适当提高维持治疗剂量,以提高吸毒人群参加社区药物维持治疗的依从性。
Objective To explore the status of retention and related factors of community-based methadone maintenance treatment （MMT） among drug users in Jiangsu province. Methods Local heroine-dependent people were admitted to community-based MMT program with national MMT guideline. Data on outpatients＇ demographic characteristics, durg use behaviors and daily stabilized dose of drugs were entered to national MMT database and analyzed by survival analysis method. Results There were 590 drug users withdrawing MMT treatment among 1 358 heroin-dependent drug users and the median length of stay in MMT was 603 days. One year and two year maintenance probability were 72. 81% and 52.67% ,respectively. Gender,marriage status, age at the first drug use and stabilized dose had significant effect on maintenance of MMT in multiple Cox proportional hazard regression model. Conclusion Retention of MMT among drug users was very high in Jiangsu province, but after 24 months the retention dropped rapidly. Patients should be given more individual counseling and social help and higher dose within the ranges of clinic dosage to increase the compliance rate.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2009年第7期779-780,共2页
Chinese Journal of Public Health
基金
江苏省科技厅基金(BS2006078)
关键词
吸毒者
美沙酮维持治疗
生存分析
drug user
methadone maintenance treatment
survival analysis
