摘要
目的探讨肝癌切除术对原发性肝癌并发破裂出血患者生存期的影响。方法采用Kaplan-Meier生存分析方法,随访期为5年,对行肝癌切除术的20例及接受非手术治疗的16例患者的生存期进行分析。结果手术组患者有3例在出血后1个月内死亡(占15.0%),该组患者的中位生存期(即有一半患者能活过的生存期)为9个月,95%可信区间(CI)为(0.26-17.77),最长生存期在52个月以上(删失);非手术组有6例在出血后1个月内死亡(占37.5%),改组患者中位生存期仅为2个月,95%CI为(0.00-4.61),最长生存期为16个月(无删失);两组患者的生存期差异具有统计学意义(2=4.516,P=0.034)。结论原发性肝癌并发破裂出血接受手术治疗患者的生存期显著长于非手术组,该病患者如条件许可应尽可能行肝癌切除术。
Objective To observe the survival time of the patients with hepatocellular carcinoma （HCC） complicated with ruptured hemorrhage treated by carcinectomy. Methods A 5-year follow-up was undertaken. There were 20 patients suffered from HCC complicated with ruptured hemorrhea and received carcinectomy, and there were 16 ones received non-surgical treatment. The survival time of the upper two groups were analyzed through Kaplan-Meier methods. Results FOR carcinectomy group, there were 3 cases died in 1 month（15%）, the median for survival time（the point in time when 50% patients could survive） was 9 months, the 95% confidence interval（CI） was（0.26-17.77）and the longest life span was more than 52 months（censored）. For non-surgical group, there were 6 cases died in 1 month （37.5%）, the median for survival time was only 2 months, the 95% CI was （0.00--4.61）and the longest life span was 16 months（non-censored）.The difference of survival time between the two groups was statistically significant（ 2=4.516, P=0.034）. Conclusion The survival time of the patients who received carcinectomy was longer than that of patients received nonsurgical treatment. It is essential and emergency to take carcinectomy for the patients with hepatocellular carcinoma （HCC） complicated with ruptured hemorrhea if the conditions permit.
出处
《医学信息》
2009年第7期1263-1265,共3页
Journal of Medical Information
关键词
原发性肝癌
并发症
肝癌切除术
生存分析
Hepatocellular carcinoma
Complications
Carcinectomy
Survival analysis
