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原发性肝癌自发性破裂出血介入动脉栓塞治疗 被引量:25

Angio-interventional treatment on spontaneous rupture and bleeding of primary liver carcinoma
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摘要 目的:研究原发性肝癌自发性破裂出血介入动脉栓塞治疗的方法.方法:回顾性分析对18例肝癌破裂出血患者采用急诊介入栓塞止血.结果:本组18例患者均得以有效止血.1例患者在3天后由于严重休克肝动脉栓塞治疗死于肝、肾衰竭.其余均无复发出血及急性肝功能衰竭.8例门静脉部分或完全阻塞患者经肝动脉栓塞(TAE)治疗后未出现肝功能衰竭.5例患者在栓塞术后3~7天内成功被施行肝肿瘤切除术.12例患者被明胶海绵栓塞术后,根据病情多次行介入治疗,肿瘤均有不同程度的缩小和坏死.结论:TAE是治疗肝癌破裂出血的有效方法,可达到立即止血的目的,同时可为肝癌后续血管内治疗提供途经. Purpose:To summarize the experiences of angio-interventional treatment on spontaneous rupture and bleeding of primary liver carcinoma. Methods:Emergency angio-interventional embolic treatment on 18 patients with spontaneous rupture and bleeding of primary liver cancer were analyzed retrospectively. Results:Hemorrhage stopped effectively in all 18 cases. One hemorrhagic shock case died of hepatic and nephric function failure after three days’ transcatheter arterial embolization (TAE) treatment. There were no recurrent hemorrhage and acute hepatic function failure after the treatment in the rest of the cases.3 to 7 days after embolization,hepatectomy was performed successfully in 5 patients and none of them died.Repeated interventional embolic treatments were performed according to patients’ conditions in the other 12 cases, and there were regression and necrosis in carcinomas to different degrees. Conclusions:TAE is an effective method of therapy for spontaneous rupture and bleeding of primary liver carcinoma because of its good hemostatic effect.
出处 《中国癌症杂志》 CAS CSCD 2005年第3期285-287,共3页 China Oncology
基金 国家教委回国人员启动基金资助项目(20010201-0312)。
关键词 原发性肝癌破裂 自发性破裂出血 介入治疗 Primary liver cancer spontaneous rupture bleeding angio-interventional treatment
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参考文献2

  • 1Yao XP, Wu MC. Bleeding from spontaneous rupture of primary hepatocellular carcinoma[A].In:Tang ZY, Wu MC , Xia SS eds. Primary Liver Cancer[M]. Beijing: China Acad Publ, BerLin : Springer, 1989: 404-405 .
  • 2Dohr O, Paine MJ, Friedberg, T , et al. Engineering of a functional human NADH-dependent cytochrome p450 system[J].Proc Natl Acad Sci U S A,2001,98(1): 81-86.

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