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Graves病淋巴细胞白介素2受体及转铁蛋白受体的表达

Studies on the lymphocyte interleukin-2 receptors and the transferrin receptors in patients with Graves disease
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摘要 应用卵白素·生物素·过氧化物酶复合物(ABC)法检测54例Graves病患者外周血淋巴细胞IL-2R,CD25及TfR,CD71的表达。结果表明,Graves病亢进期患者IL-2R与TfR均显著高于正常对照组(P<0.001),缓解期IL-2R及TfR迅速恢复(与亢进期比,P<0.001),但IL-2R仍高于正常对照组(P<0.001),而TfR与正常对照组差异无显著性(P>0.05),IL-2R与T3(r=0.5868,P<0.01),T4(r=0.4985,P<0.01)呈正相关,TfR与T3(r=0.4852,P<0.01),T4(r=0.4238,P<0.01)呈正相关。 The peripheral lymphocyte interleukin-2 receptors in patients with Graves (IL-2R) and the transferrin receptors (TfR) in patients with Graves were tested by avidin, biotin and peroxidase compound method (ABC method). Results showed that the IL-2R and TfR in patients with Graves disease were significantly higher than the control group (P<0.001) in the hyperfunction stage. Morever,in the remission stage, IL-2R and TfR recovered rapidly (P<0.001, compared to the hyperfunction stage). And compared to the normal control group, IL-2R was still higher (P<0.001) and TfR was nearly the same (P>0.05). IL-2R and T 3 (r=0.5868, P<0.001), T 4(r=0.4985, P<0.001) appeared positive correlation, TfR and T 3 (r=0.4852, P<0.01), T 4 (r=0.4238, P<0.01) also had positive correlation. The changing significance of IL-2R and TfR is discussed too.
作者 王民登
出处 《右江民族医学院学报》 1998年第2期177-179,共3页 Journal of Youjiang Medical University for Nationalities
关键词 白细胞介素2 受体 转铁蛋白 突眼性甲状腺肿 Graves disease receptors,interleukin-2 receptors, transferrin
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  • 1Z. Eisenstein,E. Engelsman,M. Weiss,Y. Kalechman,B. Sredni. Production of and response to interleukin-2 in Graves’ disease[J] 1988,Journal of Clinical Immunology(5):349~355

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