摘要
目的对比埃索美拉唑针剂和奥美拉唑针剂治疗上消化道溃疡出血的疗效。方法回顾性分析我院2007年10月至2008年10月收治的80例上消化道出血患者的临床资料。结果埃索美拉唑组pH值升高程度大于奥美拉唑组,有显著性差异,P<0.05。两组疗效经÷2检验,÷2=1.62,P>0.05,相比差异无统计学意义。两组不良反应发生率差异有统计学意义(÷2=5.54,P<0.05)。结论应用埃索美拉唑治疗溃疡性上消化道出血,能在短时间内控制上消化道出血,提高胃内pH值,临床疗效显著,无明显不良反应,可安全应用于上消化道溃疡出血的临床治疗,效果明显强于奥美拉唑。
Objective To compare the efficacy of esomeprazole and omerazole in treatment of upper digestive tract ulcer bleeding. Methods The clinical data of eighty cases with upper digestive tract ulcer bleeding in our hospital from October 2007 to October 2008 were analyzed retrospectively. Results After treatment, the increasing amplitude of gastric pH value in the esomeprazole group was higher than in the omerazole group （P〈0.05）. No statistical difference was observed in efficacy between the two groups（X2=1.62, P〉 0.05）, but there was significant difference in the rate of adverse reactions between the two groups（X2=5.54, P〈 0.05）. Results Esomeprazole can increase gastric pH value quickly in a short time and control upper gastrointestinal bleeding effectively with few obvious adverse reactions. So esomeprazole is better than omerazole in treatment of upper digestive tract ulcer bleeding.
出处
《中国医药指南》
2009年第11期41-41,40,共2页
Guide of China Medicine
