摘要
目的:总结原发性醛固酮增多症(PA)的诊治经验。方法:回顾性分析手术证实的42例PA患者的临床资料。结果:血钾值与血浆醛固酮(Ald)浓度及病程长短的决定系数r2分别为0.26、0.09(P分别为0.07、0.03),病灶大小与Ald、肾素(PRA)及ARR(血浆Ald/PRA比值)的相关系数r分别为0.56,0.48,0.09(P>0.05)。B超、CT、MRI对病灶定位准确率分别为76.9%、96.2%、100%;定性准确率分别为53.5%、76.9%、93.8%。结论:血钾值与Ald浓度不具有相关性但与病程长短相关,病灶大小与血Ald,PRA及ARR不具有相关性。CT和MRI检查可提高疾病的诊断率。PA的病因决定其治疗方案。
Objective： To summarize the experiences of diagnosis and treatment of primary aldosteronism （PA）. Methods： Clinical data of 42 patients identified as PA by operation were analyzed retrospectively. Results： The ＂r^ 2 ＂of the serum potassium, plasma concentration of aldosteronism and the duration of the illness were 0. 26 and 0. 09 （P was 0. 07 and 0. 03 respectively）. The correlation coefficient （r） of size of foci and AID and ARR （ALD/ PRA ratio） were 0. 56,0. 48 and 0. 09 respectively （P〉0. 05）. The accuracy rates of ultrasonography, computer tomography （CT） and magnetic resonance imaging （MRI） were 76. 9 %,96. 2 % and 100 % for localization of loci, and the accuracy rates of qualitative determination were 53. 5% ,76. 9% and 93.8% respectively. Conclusions： The serum potassium is not correlated with the plasma concentration of aldosteronism, but it＇s related to duration of course of the disease. The size of foci isn＇t correlated to AID, PRA and ARP. CT and MRI examinations can enhance the diagnosis rate of PA. The therapy depends on the etiology of PA.
出处
《内科急危重症杂志》
2009年第3期135-137,共3页
Journal of Critical Care In Internal Medicine
