3Ray WA, Chung CP, Murray KT,et al. Atypical anfipsychotie drugs and the risk of sudden cardiac death. N Engl J Med, 2009,360 ( 3 ) : 225 - 235.
4Kongsamut S, Kang J, Chen XL. A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs. Eur J Pharmaco,2002,450( 1 ) :37 -41.
5Haddad PM, Anderson IM. Antipsychotic - related QTc prolongation, torsade de pointes and sudden death. Drugs,2002,62 ( 11 ) : 1649 - 1671.
6Harrigan EP, Miceli JJ, Anziano R, et al. A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition. J Clin Psychopharmacol, 2004,24 (1) :62 -69.
8Lieberman JA, Stroup TS, McEvoy JP, et al. Effectiveness of antip- sychotic drugs in patients with chronic schizophrenia. N Engl J Med, 2005,353 ( 12 ) : 1209 - 1223.
9Schneider KS, Tariot PN, Dagerman KS, et al. Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease. N Engl J Med,2006,355 ( 15 ) : 1525 - 1538.
10Aparasu RR, Bhatara V, Gupta S. US national trends in the use of antipsychotics during office visits, 1998 -2002. Ann Clin Psychiat, 2005,17(3) :147 -152.
6Kane JM, Leucht S, Carpenter D, et al. The expert consensus guideline series. Optimizing pharmacologic treatment of psychotic disorders.Introduction: methods, commentary, and summary. J Clin Psychiat, 2003,64 (suppl 12) : 5 -19.
7陈灏珠.实用内科学.13版.北京:人民卫生出版社,2009:1030-1031.
8Breier A, Buchanan RW, Irish D, et al. Clozapine treatment of outpatients with schizophrenia: outcome and long - term response patterns. Psychiatr Serv, 2000, 51 (10) :1249 - 1253.
9Gaszner P, Makkos Z. Clozapine treatment of schizophrenia. Neuropsychopharmacol, 1999, 1 (26) : 28 - 30.
10Meltzer HY, Alphs L, Green AI, et al. Clozapine treatment for suicidality in schizophrenia: international suicide prevention trial (Inter- SEPT) . Arch Gen Psychiat, 2003, 60( 1 ) : 82 -91.