摘要
目的探讨黄芪注射液配合常规疗法治疗支气管哮喘急性发作的疗效及其作用机制。方法将108例支气管哮喘急性发作期患者随机分为常规治疗组和联用黄芪治疗组(黄芪治疗组),黄芪治疗组在常规疗法的基础上联用黄芪注射液治疗。观察2组临床疗效并检测肺活量(FVC)、1s用力呼气容积(FEV1)和高峰呼气流速(PEF)反映患者气道反应性的3项指标在治疗前后的变化。结果黄芪治疗组显效率为68.42%,常规治疗组显效率为52.94%,差异有统计学意义(P<0.05)。黄芪治疗组FVC、FEV1和PEF治疗前后改善明显高于常规组(P<0.05或<0.01)。结论在常规治疗的基础上联用黄芪注射液治疗支气管哮喘急性发作能明显提高临床疗效,这与黄芪注射液能明显降低患者的气道高反应性有关。
Objective To observe the therapeutic effect of Huangqi injections combined with routine therapy on acute attack of bronchial asthma, and to investigate its mechanism. Methods 108 patients with acute attack of bronchial asthma were randomly divided into two groups. The patients in routine treatment group were treated by conventional therapy, however, the patients in Huangqi treatment group, on the basis of routine treatment,were treated with Huangqi injection. The therapeutic effects were observed and the three indexes of airway reactivity including FVC, FEV1 and PEF were detected for both groups. Results The effective rate in Huangqi treatment group was 68.42%, which was 52.94% in routine treatment group, there was a significant difference between two groups （ P 〈 0.05 ）. After treatment the improvement of levels of FVC, FEV1 and PEF in Huangqi treatment group was significantly obvious than that in routine treatment group（ P 〈 0.01 ）. Conclusion Huangqi injection combined with routine treatment can increase the therapeutic effect on acute attack of bronchial asthma, which is related with that Huangqi injection can obviously decrease the airway hyperreactivity in patients with acute bronchial asthma.
出处
《河北医药》
CAS
2009年第10期1166-1167,共2页
Hebei Medical Journal
关键词
支气管哮喘
黄芪注射液
临床疗效
气道高反应性
bronchial asthma
Huangqi injection
clinical efficacy
airway hyperreactivity
