摘要
目的通过分析鲍曼不动杆菌耐药性的变化,为临床治疗鲍曼不动杆菌感染提供帮助。方法收集2000年1月-2006年12月我院所分离出的菌株,采用Kirby-Bauer琼脂扩散法进行药敏试验。结果鲍曼不动杆菌2000-2005年每年分离出的菌株数在61～104株之间,占分离菌株数的第7到第10位。2006年分离出247株鲍曼不动杆菌,占分离菌株的第5位。2000-2002年,鲍曼不动杆菌对丁胺卡那、头孢哌酮/舒巴坦和亚胺培南的耐药率很低;到2003年,则只有亚胺培南的耐药率不到20%。2005和2006年,亚胺培南的耐药率也高达40%以上。结论鲍曼不动杆菌耐药现象呈明显上升趋势,需引起临床关注。
Objective To analyse the changes of antimicrobial resistance of acinetobacter baumanrtii, and provide useful help to the treatment of acinetobacter baurnannii infection. Methods The strains isolated from our hospital were collected from 2000 to 2006, and drug sensitive test were carried by Kirby-Bauer agar diffusion method. Results The strains of acinetobacter baumannii isolated from 2000 to 2005 were arranged from 61 to 104 and ranked from 7 to 10.247 strains were isolated and ranked 5 in 2006. The rates of antimicrobial resistance of acinetobacter baumannii to amikacin, cefoperazone sulbactam and imipenam were low from 2000 to 2002. But the resistant rates were not lower than 20% except for imipenam in 2003. The resistant rate of acinetobacter baumannii to imipenarn was over than 40% during 2005 and 2006. Conclusion The infections caused by acinetobacter baumannii showed a remarkable uptrend. It should be paid more attentions to the problems of multi-drug resistant and pan-resistant acinetobacter baumaxmii.
出处
《实用药物与临床》
CAS
2009年第3期212-213,共2页
Practical Pharmacy and Clinical Remedies
