摘要
目的分析不同绝经年限女性高血压患者的血脂特点。方法将410例女性高血压患者按绝经年限分为四组：A组28例，未绝经；B组131例，绝经〈18年；C组116例，≥18年绝经〈24年；D组135例，绝经≥24年。对比各组之问年龄和血脂水平的临床差异。结果绝经各组患者年龄逐渐增加，各项血脂水平也增加，与未绝经组比较差异有统计学意义（P〈0．01）。总胆固醇、甘油三酯、低密度脂蛋白胆固醇（LDL—C）、载脂蛋白B（ApoB）、高密度脂蛋白胆固醇（HDL—C）和载脂蛋白A（apoA）均表现为先增加，但随绝经年限增加又逐渐减低（P〈0．01）。LDL—C和ApoB异常率均表现为先增加后下降的趋势（P〈0．05）。结论女性高血压患者的血脂异常受绝经及其绝经年限的影响。
Objective To analyze the characteristics of blood lipid on distinct menostasis time in hypertension patients. Methods 410 female hypertension patients were divided into four groups according to menostasis time. A group 28 cases were premenopausal women;B group 131 cases were menostasis 〈 18 year;C group 116 cases were menostasis ≥18 year and 〈 24 year;D group 135 cases were menostasis≥24 year. To analyze their distinction in age and blood lipid. Results To compare with A group, the age of A, B and C group was gradually increased, there was markedly different among every group （ all P 〈 0.01 ） , and the levels of total cholesterol, triglyceride, low-density lipoprotein cholesterol （LDL-C） , apolipoprotein B（ Apo B ）, high-density lipoprotein cholesterol （HDL-C） and apolipoprotein A （Apo A ） were all in- creased ,then were gradually decreased according to menostasis time （all P 〈 0. 01 ）. Abnormality rate of LDL-C and Apo B all were respectively up then down in four groups （ all P 〈 0.05 ）. Conclusion The Abnormality of blood lipid on female hypertension patients is influenced by menostasis and age.
出处
《临床内科杂志》
CAS
2009年第6期389-391,共3页
Journal of Clinical Internal Medicine
关键词
高血压病
绝经
血脂
雌激素
Hypertension
Menostasis
Blood lipid
Estrogen
