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小儿肺炎血浆一氧化氮、超氧化物歧化酶及丙二醛测定与临床意义

CLINICAL SIGNIFICANCE OF THE TEST OF NO, SOD AND MDA IN THE PLASMA FOR INFANTILE PNEUMONIA
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摘要 本文对48例肺炎极期患儿血浆NO、SOD及MDA进行了检测,结果表明轻、重症肺炎极期血浆NO、MDA明显高于正常对照组(P<0.01),SOD明显降低(P<0.01),重症肺炎改变较轻症明显。提示:NO和氧自由基是肺炎时肺损伤的重要致病因素,且与病情严重程度有明显关系,左肺炎治疗中要辅以抗氧化剂治疗。 Test of NO, SOD and MDA in blood plasma was performed for the treatment of 48 cases of critical infantile pneumonia, showing that No and MDA in plasma for both mild and severe critical pneumonia are clearly increased (P<0. 01 ), while SOD is obviously dereased (P<0. 01 ) compared with those in the control group. It is indicated that NO and FR (oxygen free radical) are important factors for pulmonary injury when pneumonis occurs, and the severeness of the disease matters evidently. Thus, anti-oxidant should be added for the treatment of pneumonia.
作者 肖红 刘仿
出处 《综合临床医学》 1998年第3期238-239,共2页
关键词 肺炎 一氧化氮 超氧化物歧化酶 丙二醛 儿童 Infantile pneumonia Nitric oxide Oxygen free radical
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