摘要
目的 探讨小儿充血性心力衰竭 (CHF)时血浆一氧化氮 (NO)的变化及意义。方法 测定先天性心脏病合并CHF组 17例与健康小儿作对照组 15例、支气管肺炎 (支肺炎 )合并CHF组 16例与支气管肺炎组 15例及支肺炎合并CHF纠正前后的血浆NO水平。结果 先天性心脏病合并CHF组的血浆水平高于对照组且差异有非常显著意义 (P <0 0 0 1) ,支肺炎合并CHF组 (CHF纠正前 )的血浆NO水平高于支肺炎组且差异有非常显著意义 (P <0 0 0 1)。结论 CHF患儿的血浆NO水平升高是CHF患儿的病理生理特征之一 ,NO参与CHF的病理生理 ,可作为判断CHF的一个辅助指标。
Objective To study the effect of plasma nitric oxide(NO) levels on children with congestive heart failure(CHF).Methods The plasma NO was measured in 16 children with CHF due to congenital heart desease(CHD) and 15 healthy children as control group,16 children with CHF due to bronchopneumonia and 15 children with bronchopneumoina.Results The plasma NO of children with CHF due to CHD and bronchopneumonia increased remarkably comparied with the control group and children with bronchopneumonia(P<0.001).Conclusion NO plays important role in the pathophysio logic change of CHF.The plasma NO can be used as a parameter of CHF.
出处
《中国基层医药》
CAS
2003年第2期126-127,共2页
Chinese Journal of Primary Medicine and Pharmacy
