摘要
应用放射免疫技术测定了胃癌患者血清层粘连蛋白（LN）水平变化及切除肿瘤对其的影响。结果显示：胃癌患者血清LN水平明显高于对照组（P＜0．05）；进展期组高于早期组（P＜0．O5〕；手术切除肿瘤特别是行根治性切除术后，血清LN水平显著降低P＜O．05）。认为血清LN水平与肿瘤的浸润及转移过程密切相关；观察血清LN水平及其变化，对胃癌者的病情及预后判断有一定的参考价值。
The contents of laminin(LN)in serum were measured by radioimmunoassay in patients with gastric cancer before and after resection of the tumor. It was showed that thecontent of LN in cancer group was significantly higher than that in control group (P<0.05),and the content in advanced stage group was much higher than that in early stagegroup (P<0.05). After resection of the tumor the content of LN was decreased significantly, especially in radical resection group (P<0.05). This implies that the content ofserum LN is closely related to the tumor invasion and metastases,and the assay of LN inserum may be useful to the diagnosis of gastric cancer.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1998年第3期181-182,185,共3页
Cancer Research on Prevention and Treatment
关键词
层粘连蛋白
外科手术
胃肿瘤
gastric cancer
laminin
radioimmunoassay
serum
