摘要
目的:观察全身伽玛刀配合甘氨双唑钠治疗食管癌术后复发的临床效果。方法:食管癌术后出现局部复发患者78例,随机分为实验组和对照组。实验组(38例),采用甘氨双唑钠0.75g,每周给药3次+放疗;对照组(40例),采用单纯放疗,用50%～85%的等计量曲线包绕靶区,总计量35～40Gy,分割成10～12次。结果:有效率:CR+PR为89.4%,62.5%,P<0.05。两组不良反应差异无显著性。结论:甘氨双唑钠对食管癌术后局部复发患者的放疗有较好的临床放射增敏作用,值得推广。
Objective：To discuss the curative effect of whole body T-knife and CMNa therapy on recurrent esophageal earoinoma after operation. Methods：78 patients were divided into radiotherapy （RT） plus CMNa group and RT alone group radomly. The RT plus CMNa group （38 cases） was given CMNa 0.75 g three times a week. The control group was used RT alone.The targets was covered with 50%-85% isodose curve.The total radiation dosage was 35-40 Gy,divided into 10-12 times.Results：In RT plus CMNa and RT group. the effective rate was （CR,PR） 89.4% and 62.5%,P〈0.05.There was no significant differenee on toeixity in two groups.Conelusion：CMNa is effective to enhance tumor radiation sensivity in recurrent esophageal carcinoma after operation.
出处
《现代医药卫生》
2009年第11期1608-1609,共2页
Journal of Modern Medicine & Health
关键词
食管癌术后复发
伽玛刀
放射治疗
甘氨双唑钠
Recurrent esophageal carcinoma after operation
T-knife
Radiotheapy
CMNa
