摘要
为评价食管癌术后颈部和纵隔淋巴结转移局部放射治疗的意义，回顾性分析1989年3月～1994年2月5年间收治的143例病人。其中颈部转移89例，纵隔转移32例，纵隔和颈部同时并有转移22例。60Co局部放射，大多数病人的放射剂量为50～70Gy。随访2年以上或至死亡。结果70％以上的肿瘤获得局部控制。1，2，3，5年生存率分别为43．4％，18．2％，7．4％和6．4％。中位生存期14个月。多数病人死于照射野外转移。转移淋巴结≤3cm者放疗后的局部控制率和生存期优于淋巴结＞3cm者。结果提示：放疗对食管癌术后颈部和纵隔转移淋巴结的局部控制有效，但只有少数病人可获较长时间生存。远处转移是致死的主要原因。
From March 1989 through February 1994, 143 cases of neck or/and mediastinal lymph node metastases presented after resection of cancer of theesophagus were treated with irradiation. A majority of the patients recieved a totalof 50-70Gy. Over 70% of the lesions were locally controlled with irradiation. The1-, 2-, 3- and 5-year survivals were 43. 45 %, 18. 2%, 7. 45 % and 6. 4 % respectively. The median survival of the patients was 14 months. Patients with metastaticlymph nodes of <3cm had better local control and longer survival than those whosenodes were > 3cm in diameter. Most of the patients eventually died from distantmetastases. It is concluded that local irradiation is effective for control of neck andmediastinal lymph node metastases after surgery of esophageal cancer. The poorlong term survival is ascribed to systemic metastases.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1997年第10期753-755,共3页
Chinese Journal of Clinical Oncology
关键词
食管肿瘤
淋巴结转移
放射疗法
Esophageal cancer Lymph node metastases Radiotherapy
