摘要
本文旨在观察二硫化碳（ＣＳ２）对接触工人促性腺激素和生精功能的影响。工人工作地点ＣＳ２平均浓度（几何均数）为３２．６０±５．１４ｍｇ／ｍ３，约高于国家容许浓度２倍，对１８例长期接触超标浓度的ＣＳ２作业工人进行了血清睾酮（Ｔ），促黄体生成素（ＬＨ），间质细胞刺激素（ＦＳＨ）测定，观察１６名工人精液的某些参数。结果表明：ＣＳ２接触组血清中ＬＨ和ＦＳＨ浓度与对照组比较，显著升高，Ｐ＜０．０１；而ＣＳ２组精子计数、血清Ｔ浓度与对照组相比，明显降低，Ｐ＜０．０５。畸形率高于对照组，但无统计学意义，本研究结果表明，ＣＳ２对接触工人性腺内分泌功能已造成一定的损伤，并降低生精功能。
The effect of carbon disulfide on gonadotropins and the spermatogenesis in workers exposed to CS_2 was studiedThe mean concentration of CS_2 in workplace was 32.60±5.14mg/m3,which was 3 fold higher than the maximal allowance concentration of national standardThe serum testosterone(T)、follicle stimulating hormone(FSH) and luteinizing hormone(LH) in 18 workers and some parameters of semen in 16 workers were measuredThe results showed:serum T level in CS2 group(1748±341mmol/L) was significantly lower than that of control (2307±551mmol/L),P<005In addition,LH(829±123IU/L)、FSH(752±281IU/L) in CS2 group were significantly higher than those in control,which were 559±086IU/L and 395±109IU/L respectively,P<001Sperm count in workers of CS2 group was decreased when compared with that of control,P<005The frequency of abnormal sperms in morphology was higher than that of control,but there was no statistical significanceThe results suggested that both the endocrine functions and gonad organ were disturbed in workers exposed to higher level of CS2,consequestly the spermatogenesis was decreased
出处
《职业医学》
1998年第1期6-7,共2页
China Occupational Medicine
基金
中华医学基金会(CMB)资助
关键词
性腺激素
生精
二硫化碳
工人
functions of endocrine and gonad organ,spermatogenesis,carbon disulfide
