摘要
EB病毒（EBV）是一种DNA肿瘤病毒，以往有关EBV致瘤机制的研究主要集中在B淋巴细胞。目前检测发现人类T细胞淋巴瘤也存在EBV感染。近年来研究表明EBV感染可转化T淋巴细胞，EBV可能在T细胞淋巴瘤的发生中起重要作用。观察LMP1在T细胞中的分子生物效应，有助于了解T淋巴细胞中EBV的感染途径、感染方式以及T细胞淋巴瘤的发生机制。
Epstein-Barr vires （EBV） is a kind of DNA tumor virus. Previous Studies on the tumorigenic mechanism of EBV mainly focus on human B lymphocyte. Now there are evidences that EBV exists in human T-cell lymphoma. Exploration in recent years show that EBV could infect T lymphocyte and likely play an important role in the pathogenesis of T-cell lymphoma. Investigation of molecular biological effect of LMP1 in T cell will be helpful for us to understand the approach and mode of EBV infecting T lymphocyte as well as the mechanism of T-cell lymphoma development.
出处
《白血病．淋巴瘤》
CAS
2009年第5期312-315,共4页
Journal of Leukemia & Lymphoma
