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小于胎龄儿营养程序化与成人代谢综合征 被引量：11

Nutritional Programming in Small for Gestational Age Infants and Metabolic Syndrome in Adult
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摘要 小于胎龄儿(SGA)是成人代谢综合征(MS)的高危人群。SGA由于对宫内不利营养环境的适应性改变,导致机体多种激素重整,尤其是产生胰岛素抵抗并持续至成年期,使SGA罹患2型糖尿病等代谢综合征的易患性增加。利用"营养程序化"的作用,在出生早期生长发育的敏感时期予SGA高蛋白等热能饮食的营养干预,有可能避免胰岛素抵抗或减轻其程度,降低SGA在成年后发生MS的易患性。
作者 丘小汕
机构地区 中山大学附属第一医院儿科
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2009年第7期488-490,共3页 Journal of Applied Clinical Pediatrics
关键词 营养 程序化 代谢综合征 小于胎龄儿
分类号 R722 [医药卫生—儿科] R589 [医药卫生—内分泌]
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参考文献19

  • 1宋秀霞 ,纪立农 .国际糖尿病联盟代谢综合征全球共识定义[J].中华糖尿病杂志（1006-6187）,2005,13(3):178-180. 被引量：620
  • 2Barker D J, Hales CN, Fall CH, et al. Type 2 ( non - insulin - dependent) diabetes mellitus, hypertension and hyperlipidemia (syndrome X) :Relation to reduced fetal growth [ J ]. Diabetologia, 1993,36 (1) :62 -67.
  • 3Lucas A. Programming by early nutrition:An experimental approach [ J ]. J Nutr, 1998,128 (2 suppl) :401 -406.
  • 4Ozanne SE. Metabolic programming in animals[ J]. Br Med BuU,2001, 60 : 143 - 152.
  • 5Hofman PL, Cutfield WS, Robinson EM, et al. Insulin resistance in short children with intrauterine growth retardation [ J ]. J Clin Endocrinol Metab, 1997,82 ( 2 ) :402 - 406.
  • 6杜敏联.小儿营养和生长的调控及评估近展[J].新医学,1998,29(4):171-171. 被引量：2
  • 7Ketelslegers JM, Maiter D, Maes M, et al. Nutritional regulation of insulin - like growth factor - I [ J]. Metabolism, 1995,44 ( 10 suppl 4 ) : 50 -57.
  • 8Withers D J, Burks DJ,Towery HH,et al. Irs - 2 coordinates IGF - 1 receptor - mediated beta - cell development and peripheral insulin signaling [ J ]. Nat Genet, 1999,23 ( 1 ) : 32 - 40.
  • 9贲晓明,喻文亮,秦玉明,蔡威,张伟利,吴圣楣.新生儿脐血瘦素水平及其相关因素的探讨[J].中国儿童保健杂志,2000,8(6):375-377. 被引量：4
  • 10Islam MS, Morton NM, Hansson A, et al. Rat insulinomaderived pancreatic beta - cells express a functional leptin receptor that mediates a prodiferative response [ J ]. Biochem Biophys Res Commum, 1997,238 (3) :851 -855.

二级参考文献66

  • 1李光伟,Step.,L.检测人群胰岛素敏感性的一项新指数[J].中华内科杂志,1993,32(10):656-660. 被引量：2127
  • 2[1] Susan MS, Darlise MO, Jennifer J, et al. Leptin expression in human mannart epithelial cells and breast milk[J] .J Clin Endocrinol Metab,1998,83(5): 1810-1813.
  • 3[2] Considine RV. Sinda BX, Heinen ML, et al. Serum immuoreactive concentrations in normal weight and obese humans [J]. N Engl J Med,1996,334:292-295.
  • 4[3] Koistinen HA, Koivisto VA, Andersson S, et al. Leptin concentration in cord blood correlates with intrauterine growth [J]. J Clin Endocrinol Metab 1997,82(10):3328-3330.
  • 5[4] Schubring C, Siebler T, Kratzsch J, et al. Leptin serum concentrations in healthy neonates within the first week of life: relation to insulin and growth hormone levels, skinfold thickness, body mass index and weight[J]. Clin Endocrinol(Oxf), 1999 ,51 (2): 1999-204.
  • 6[5] Compfield LA, Smith FL, Guisez Y, et al. Recombinant mouse OB pro-tein: evidence for a peripheral signal linking adiposity and central neu-ral networks[J]. Science, 1995,269: 546-549.
  • 7[6] Halass JL, Gajiwala KS, Maffei M, et al. Weight-reducing effects of the plasma protein encoded by the obese gene[ J]. Science, 1995,269:543-546.
  • 8[7] Chehab FF, Mounzih K,Lu R, etal. Early onset of reproductive funetion in normal female mice treated with leptin[J]. Science, 1997,275:88-91.
  • 9[8] Senaris R, Gareia-Caballero T, Casabiell X, et al. Synthesis of leptin in human placenta[J]. Endocrinology, 1997,138(10) :4501-4504.
  • 10Mattews DR, Hosker JP, Rudenski AS, et al.Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man.Diabetologia, 1985, 28: 412-419.

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实用儿科临床杂志
2009年 第7期

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