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出生体重与儿童胰岛素抵抗的关系研究进展 被引量：2

The Development of Relationship Between Birth Weight and Childhood Insulin Resistance
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摘要 胰岛素抵抗是指体内胰岛素作用减低的一种病理生理改变。低出生体重与新生儿期、幼儿期和青少年期胰岛素抵抗均有相关性;婴儿期的胰岛素抵抗与出生后追赶生长相关性较强,提示胎儿期和儿童早期营养环境是儿童胰岛素抵抗的影响因素之一。早期的营养干预可能影响儿童胰岛素抵抗的发病率。也有部分研究对上述结果提出异议,尚待从营养、遗传和流行病学等方面进一步探讨出生体重和胰岛素抵抗的关系及其可能的机制。
作者 王秀敏 梁黎 杜立中
机构地区 浙江大学医学院附属儿童医院内分泌科
出处 《国外医学（儿科学分册）》 2005年第5期311-313,共3页 Foreign Medical Sciences（Section of Pediatrics)
基金 浙江省科技厅重点科研国际合作项目(2005C24001)
关键词 出生体重 胰岛素抵抗
分类号 R725.8 [医药卫生—儿科]
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参考文献19

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同被引文献18

  • 1Munivappa R,Lee S,Chen H,et al.Current approaches for assessing insulin sensitivity and resistance in vivo:advantages,limitations and appropriate usage[J].Am J Physiol Endocrinol Metab,2008,294(1):15-16.
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  • 5王嘉,王秀敏,梁黎,杜立中,顾伟忠.低出生体重新生大鼠胰岛素与K^+_(ATP)通道表达的相关性研究[J].临床儿科杂志,2007,25(8):692-695. 被引量：2
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国外医学（儿科学分册）
2005年 第5期

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