摘要
本文用肝血管瘤石蜡切片作血管内皮生长因子（ＶＥＧＦ）链霉亲和素—生物素—过氧化物酶免疫组织化学染色（即ＳＡＢＣ法）和核仁组成区相关嗜银蛋白（ＡｇＮＯＲ）计数方法，研究ＶＥＧＦ在肝血管瘤成因中的地位。结果显示：４８例肝血管瘤标本中，ＶＥＧＦ阳性表达率为７５．０％，其中（＋）者９例，（）者１１例，（）者１６例，且ＶＥＧＦ表达强度在不同的组别间ＡｇＮＯＲ计数差异显著（Ｐ＜０．０１）。提示ＶＥＧＦ在肝血管瘤的成因中可能具有重要意义。
This experiment studies the role of Vascular Endothelial Growth Factor(VEGF) in the cause of hepatic hemangioma with Immunohistochemical staining (SABC) and AgNOR counting with paraffinembedded hepatic hemangioma slides The results showed that in the 48 cases of hepatic hemangioma, VEGF positive rate was 750%, with 9 cases (+), 11cases (), 16 cases (), and the difference between groups of different degrees of VEGF expression was significant (P<001) The results tend to indicate that VEGF may have a lot to do with the cause of hepatic hemangioma
