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盐酸丁卡因碱化凝胶减轻静脉穿刺疼痛的临床观察 被引量:6

CLINICAL STUDY ON THE VENIPUNCTURE PAIN ABATEMENT OF ALKALIZED GEL OF TETRACAINE HYDROCHLORIDE
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摘要 目的:观察1%盐酸丁卡因碱化凝胶减轻静脉穿刺疼痛的透皮局部麻醉效果。方法:60例拟行静脉穿刺术的病人随机分成实验组和安慰组。每组30例。将1%盐酸丁卡因碱化凝胶和安慰凝胶分别涂敷于患者手背皮肤,45min后行静脉穿刺术。采用4级口述分级法和视觉模拟评分法评估透皮局部麻醉效果。结果:1%盐酸丁卡因碱化凝胶可使疼痛分值较安慰凝胶显著下降(P<0.01),其减轻静脉穿刺疼痛作用明显优于安慰凝胶。结论:1%盐酸丁卡因碱化凝胶能为静脉穿刺提供较有效的透皮局部麻醉,具有一定的临床应用价值。 Objective.The percutanous local anesthesia effect of alkalized tetracaine hydrochloride gel on reducing the pain of venepuncture was observed: Methods:alkalized 1% tetracaine hydrochloride gel and placebo were applied to the dosum of hand respectively for a period of 45 min.After removal of the gels,venepuncture was performed.Patients assessed the pain experienced using four-point verbal rank score and visual analogue scale.Results:Statistical analysis of results indicated that there was singnificant difference in pain scores betwen two groups(P<001)and that alkalized 1% tetracaine hydochloride gel was superior to placebo.Conclusions:Alkalized 1%tetracaine hydrochlorid gel produced effctive percutanous anesthesia for venepuncture and was of clinical value.
出处 《河北医学》 CAS 1998年第1期9-11,共3页 Hebei Medicine
关键词 丁卡因 碱化凝胶 静脉穿刺 镇痛 tetracaine percutanous local anesthesin
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参考文献4

  • 1McCafferty DF.Woolfson AD.Handley J,et al.Effect of percutaneoas local anasthesia on pain reduction during pulse dys laser treatment of portwine stains.Br J Anaesth.1997;78:286.
  • 2邱瑜.局部麻醉药经皮吸收研究及其展望[J].国外医学(麻醉学与复苏分册),1996,17(5):274-276. 被引量:25
  • 3Gajraj NM,Pennant JH,Watcha MF.Eutectic Mixture of local anesthesia (EMLA)craem.Anesth Analg.1994;78:754.
  • 4Woolfson AD.McCafferty DF.McClelland KH,et al.Concentration-response analysis of percutaneoas local aneathetic formulations.Br J Anaeth.1988;61:59.

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