摘要
我们以隆线溞和微型裸腹溞为实验动物,进行了两种酚类内分泌干扰物双酚A(BPA)和壬基酚(NP)的毒性效应研究。急性实验测定出双酚A对隆线溞的24h和48h半数致死浓度(LC50)为:12.02mg/L和11.64mg/L,对微型裸腹溞24h和48h半数致死浓度LC50为:13.70mg/L和9.63mg/L。而壬基酚对隆线溞的24h和48h半数致死浓度(LC50)分别为:0.221mg/L和0.159mg/L,对微型裸腹溞的24h和48h半数致死浓度(LC50)分别为:0.334mg/L和0.126mg/L。实验表明微型裸腹溞对双酚A和壬基酚的敏感度高于隆线溞,能够很好的指示水环境的污染。慢性毒性实验发现双酚A对微型裸腹溞后代的雌雄比例有明显的影响,影响类似于hormesis现象。而壬基酚对隆线溞的慢性毒性研究发现,隆线溞的生活史、后代成活率均受到暴露的壬基酚浓度升高的不利影响庑┭芯勘砻?低浓度双酚A长期暴露的潜在毒性与高浓度壬基酚的急性毒性在这两种内分泌干扰物污染环境的研究中有重要意义。
In our experiments, Daphnia carinata and Moina micura were used as material to evaluate the toxicity of BPA and NP. From acute experiments, the 24h and 48h LCs0of D. carinata to BPA were 12.02mg/L and 11.64mg/L, the 24h and 48h LC50 of M. micura to BPA were 13.70mg/L and 9.63mg/L, respectively. The 24h and 48h LC50 of D. carinata to NP were 0. 221mg/L and 0. 159mg/L, the 24h and 48h LCs0of M. micura to NP were 0. 334mg/L and 0. 126mg/L, respectively. It indicated that M. micura was more sensitive to the toxicity of BPA and NP than D. carinata, which offers a good tool to evaluate the pollution of water environment. In chronic experiments, there is a significant relationship between the ratio of male offspring in total offspring and the exposed concentration of BPA and the effects looks like a hormesis phenomenon. The life history and the survive rate of offspring exhibited a negative correlation to the exposed concentration of NP, our results suggested that the chronic toxicity of BPA and the acute toxicity of NP were very important to evaluate the pollution of water environment by the two compounds.
出处
《水生生物学报》
CAS
CSCD
北大核心
2009年第3期492-497,共6页
Acta Hydrobiologica Sinica
基金
中国科学院知识创新工程方向项目(KZCX2-SW-129))资助
