摘要
目的:探讨脉压(PP)、脉压指数(PPI)与代谢综合征(MS)患者心脑血管疾病的相关性。方法:选择近5年我院门诊和住院MS患者204例(男138例,女66例),按PPI≤0.40、0.41~0.50、0.51~0.60、>0.60分为4组,按PP≤40 mmHg、41~60 mmHg、61~80 mmHg、>80 mmHg(1 mmHg=0.133kPa)分为4组,分析各组间PP、PPI与心脑血管疾病发生率的相关性。结果:①不同组的PP、PPI在吸烟、饮酒、体重指数(BMI)、血糖、腹围、舒张压(DBP)、甘油三脂(TG)、高密度脂蛋白-胆固醇(HDL-C)、及低密度脂蛋白-胆固醇(LDL-C)方面无显著差别(P>0.05),在年龄、收缩压(SBP)方面差异有显著性(P<0.05~<0.01);不同组的PP及PPI的左室肥厚、冠心病、心功能不全、脑卒中发生率有显著性差异(P均<0.05);左室肥厚、冠心病、心功能不全、脑卒中的发生率与患者年龄、收缩压、脉压、脉压指数有显著相关性[EXP(B)=1.614~3.340,P均<0.05]。结论:MS患者心脑血管疾病与年龄、SBP、PP、PPI等因素有关,与PPI的关系更为密切。
Objective:To investigate the correlation between pulse pressure,and cardiovascular and cerebrovascular diseases in patients with metabolic syndrome(MS).Methods:A total of 204 outpatients or inpatients with MS of our hospital in the past five years(138 male cases and 66 female cases)were chose.They were divided into four groups by PPI≤0.40,0.41~0.50.0.51~0.60,>0.60;and into four groups by PP≤40 mmHg,41~60 mmHg,61~80 mmHg.>80mmHg(1mmHg=0.133kPa).and the correlation among PP,PPI and incidence of cardiovascular and cerebrovascular diseases was analyzed.Results:There was no significant difference in smokers.drinkers.BMI.blood sugar.abdominal circumference,diastolic blood pressure(DBP),triglyceride(TG),high-density lipoprotein(HDL-C)and low-density lipoprotein(LDL-C)among the different groups divided byPPand PPI(P>0.05).there were significant differences in age and systolic blood pressure(SBP)(P<0.05~<0.01).There were significant differences in left ventricular hypertrophy,and incidence of coronary heart disease,heart failure and stroke among the different groups divided by PPand PPI(P<0.05 all).Left ventricular hypertrophy,coronary heart discase,heart failure and stroke were significantly correlated to the age,systolic blood pressure.pulse pressure and pulse pressure index[EXP(B)=1.614~3.340,P<0.05].Conclusion:The incidence of cardiovascular and cerebrovascular dis-eases in MS patients are related to their age,SBP,PP,PPI,and correlation to PPI is more closely.
作者
任春霖
胡胜利
REN Chun-lin;HU Sheng-li(Department of Cardiology,Dongfeng General Hospital,Affiliated to YunyangMedical College,Shiyan,Hubei,442008)
出处
《心血管康复医学杂志》
CAS
2009年第2期109-112,共4页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
代谢综合征X
血压
心血管疾病
脑血管意外
Metabolic syndrome X
Blood pressure
Cardiovascular disease
Cerebrovascular accident
