摘要
目的:了解我院肠球菌在临床的感染性分布,并对其耐药情况进行分析,指导临床合理有效地使用抗生素。方法:采用回顾性统计分析方法对我院2006年1月-2008年5月分离出的364株肠球菌的鉴定结果以及用Kirby-Bauer纸片琼脂扩散法检测对15种抗生素的耐药情况进行分析。结果:364株肠球菌中,粪肠球菌195株,屎肠球菌160株,鹑鸡肠球菌4株,铅黄肠球菌2株,坚韧肠球菌2株,鸟肠球菌1株。主要分布在尿154例,其次是分泌物70例,血液45例,痰液40例,导管23例,胆汁13例,腹水12例,脓液7例。除对万古霉素和替考拉宁的耐药率较低外,对大多数常用抗生素的耐药率均达50%以上。结论:泌尿系统肠球菌感染最为常见。万古霉素和替考拉宁仍是治疗肠球菌感染最有效的药物,但应结合药敏试验结果指导临床合理地选用抗生素,以减轻对万古霉素的依赖,防止其耐药菌株的产生。
Objective：To study the clinical transmissibility distribution of enterococcus isolated from Nanjing Gulou Hospital and its drug resistance in order to guide the reasonable and effective selection and use of antimicrobial agents. Method： To analyze with retrospective statistical analytical method the identification results of 364 strains of enterococcus isolated from Jan 2006 to May 2008 in our hospital and its status of drug resistance to 15 kinds of antimicrobial agents with the way of Kirby-Bauer. Result：Among 364 strains of enterococcus there are 195 strains of E. faecalis, 160 strains of E. faeeium, 4 strains of E. gallimarum, 4 strains of E. casseliflavus, 2 strains of E. durans and 1 strain of E. avium. The enterococcus were mainly distributed in urine （154）, then in secretion （70）, next in blood （45）, in spit （40）, in catheter （23）, in bile （13）, in ascetic fluid （12） and in liquor purls （7）. The rates of drug resistance of enterocoecus to the most of the antibiotics often used were above 50% except vancomycin and teicoplanin. Conclusion： Urinary infections caused by enterococcus are most common. Although vancomyein and teicoplanin are still the most effective drug for curing enterococeus infection, antibiotics should be selected reasonably according to the results of antimicrobial susceptibility test. Further more, use of vancomycin must be paid attention to prevent the increasing rate of drug resistance.
出处
《临床急诊杂志》
CAS
2009年第2期73-76,共4页
Journal of Clinical Emergency
关键词
肠
耐药性
enterocoecus
resistance
