摘要
胃癌是死亡率极高的恶性肿瘤。胃癌的早期诊断有助于发现并选择合适的治疗方案以降低其死亡率。近年来随着分子生物学技术的发展,血清学标志物以其创伤小,痛苦少而成了研究的重点。由于胃癌通常由一系列癌前疾病发展而来,因此与胃癌前病变各个阶段相关的血清学生物标志物的检测对于胃部肿瘤的早期诊断同样具有重要的临床意义。本文综述了目前胃癌前病变阶段及胃癌诊断相关的血清学生物标记物研究的最新进展。这些血清学标志物对于病情估计以及胃癌的早期诊断、组织分型及判断预后等都具有重要意义。
Gastric cancer is of extremely high mortality rate in malignant tumors. The detection of early gastric cancer is helpful for optima decisions in clinical treatments and reduction of its mortality. In recent years, with the development of molecular biology techniques, serological markers became the focus of the study because of its advantage of less trauma and pain. Because gastric cancer is usually a series of precancerous disease, serum markers detection which is related with all stages of gastric precancerous lesions has been attached great clinical importance. This review focused on the current progresses in serum markers of gastric precancerous lesions and gastric cancer. These serological markers are of important significance for the estimation of diseases, and the early diagnosis, histological type classification as well as prognosis evaluation of gastric cancer
出处
《现代生物医学进展》
CAS
2009年第7期1377-1380,共4页
Progress in Modern Biomedicine
基金
上海市科委2007年研发公共服务平台建设项目(071422007)
关键词
胃癌前病变
胃癌
血清学标志物
Gastric precancerous lesions
Gastric cancer
Serum markers
