摘要
目的:探讨螺旋藻对D-半乳糖所致学习、记忆障碍的改善作用。方法:使用D-半乳糖建立小鼠衰老模型,用螺旋藻灌胃进行实验性治疗。持续6w后,通过跳台实验、避暗实验和Morris水迷宫实验检测小鼠的学习记忆能力。结果:与对照组相比,模型组小鼠的学习、记忆能力下降(p<0.05或p<0.01);与模型组相比,治疗组的学习、记忆能力又不同程度的得到恢复(p<0.05)。结论:螺旋藻可改善由D-半乳糖所导致的学习、记忆障碍。
Effect of Spirulina on learning and memory disturbance on aging mice model induced by D-galactose by gavage was investigated. Following by six-week administration, the ability of learning and memory was assessed by step-down test, dark avoidance test, water-maze spatial localization task. Results indicated that the ability of learning and memory in model group decreases （p 〈 0.05 or p 〈 0.01）, and this ability is recovered in different degrees following by Spirulina feeding （p 〈 0.05）. In conclusion, Spirulina is favorable for the recovery of learning and memory disturbance in aging mice.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2009年第7期236-238,共3页
Food Science
关键词
螺旋藻
衰老
记忆障碍
改善作用
Spirulina
aging
memory disturbance
improvement
