摘要
目的:观察单纯性肥胖伴暴食行为者、肥胖饮食正常者及正常体质量者胃排空速率,并探讨三者胃排空速率的变化特征.方法:采用SPECT(单光子发射计算机扫描),对42例单纯性肥胖伴暴食行为者32例饮食正常者及40例正常体质量健康志愿者进食99mTc-DTPA标记的实验餐后胃部图象采集,按公式计算出胃半排空时间及各时相胃排空率.结果:单纯性肥胖伴暴食行为组较正常体质量组胃半排空时间明显缩短(71.21±19.2min vs81.25±14.08min,P<0.01).单纯性肥胖饮食正常组较正常体质量组胃半排空时间无明显差别.单纯性肥胖伴暴食行为组较正常体质量组各时间段胃排空率明显加快(30min:22.35%±4.53%vs15.82%±4.72%;60min:55.13%±9.21%vs47.25%±8.18%;90min:76.35%±5.76%vs69.29%±8.85%;120min:92.22%±7.41%vs84.92%±6.53%,均P<0.01),单纯性肥胖饮食正常组与正常体质量组各时间段胃排空率比较无明显差异.结论:单纯性肥胖伴暴食行为者胃排空速率加快,这可能是导致肥胖的一个重要原因.
AIM： To observe gastric emptying rates in simple obesity accompanied by bulimia, simple obesity with normal diet and normal weight people, and to investigate the characteristics of gastric emptying.METHODS： Forty two subjects with simple obe- sity accompanied by bulimia, 32 subjects with simple obesity and normal food intake and 40 people with normal weight were studied with SPECT. After subjects eating test meal marked 99mTc-DTPA, picture of stomach was collected, and gastric emptying rate was calculated according to a fixed formula.RESULTS： Gastric emptying halftime of simple obesity accompanied by bulimia was shorter than that of normal control （71.21 ± 19.2 min vs 81.25 ± 14.08 min, P 〈 0.01）. Gastric emptying halftime of normal food intake group was similar to that of normal control group. Gastric emptying rate of simple obesity with bulimia was quicker than normal control （30 min： 22.35% ± 4.53% vs 15.82% ± 4.72%; 60 min： 55.13% ± 9.21% vs 47.25% ± 8.18%; 90 min： 76.35% ± 5.76% vs 69.29% ± 8.85%; 120 min： 92.22% ± 7.41% vs 84.92% ± 6.53%, all P 〈 0.01）. Gastric emptying rate of normal food intake group was similar to that of normal control group.CONCLUSION： The gastric emptying rate in simple obesity with bulimia become is quicker, which may partly account for obesity.
出处
《世界华人消化杂志》
CAS
北大核心
2009年第7期705-707,共3页
World Chinese Journal of Digestology
关键词
单纯性肥胖
单光子发射计算机扫描
胃排空
Simple obesity
Single-photon emissioncomputed tomography
Gastric emptying
