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新型自张式外周血管支架的初步实验研究

Self-expanding endovascular prosthesis:a preliminary study
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摘要 目的:对自制的外周血管支架进行评估。方法:经皮股动脉途径,植入新型设计的自张式支架至成年犬的髂动脉(6条)和股动脉(3条),观察一个月后血管造影及组织学变化。结果;所有支架均成功地植入到犬的外周动脉内,造影显示管腔开通良好。光镜下,支架段血管完全内皮化,支架丝被覆薄层新生内膜。结论:此支架具有较好的顺应性、可视性、释放系统简单。 Objective To assess the effect of a self-expanding,endovascular prosthesis. Methods A novel, self- expanding endovascular stent was implanted into adult canine iliac(n = 6)and femoral (n = 3)ar-teries. Animals were sacrificed,and vessels were perfusion-fixed 28 days post-procedure. Results Arterio-graphically ,stented vessels were without stenosis. Histologically ,the stent was coverd by neointima. Most of stent struts abut the vessel wall and compress the media v/ithout laceration of the internal elastc lamina. Conclusion This novel stent was radiopaque and easily implantable. The stent might be worthy for further development.
出处 《中国微创外科杂志》 CSCD 1999年第4期15-16,62-64,共4页 Chinese Journal of Minimally Invasive Surgery
关键词 支架 新生内膜 stent Neointima
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