摘要
刺激杏仁外侧核或基底核，可在兔听区皮层观察到诱发电位，诱发电位分布在ＷｏｏｌｓｅｙＡⅠ、ＡⅡ区及嗅鼻沟后缘听区皮层（ＡＣＢＲＳ区），以ＡＣＢＲＳ区反应为最大。诱发反应的潜伏期最短为２毫秒，表明杏仁向听皮层的投射可能是单突触的。形态学工作揭示，兔主要听区ＡＣＢＲＳ区电泳辣根过氧化物酶（ＨＲＰ），杏仁外侧核及基底核都观察到逆行标记细胞，标记细胞数量以杏仁外侧核为多；ＷｏｏｌｓｅｙＡⅠ、ＡⅡ区电泳ＨＲＰ，仅在杏仁外侧核观察到少量逆行标记细胞，说明发出杏仁听皮层投射的主要是杏仁外侧核，杏仁投射部位以兔主要听区ＡＣＢＲＳ区为主。这一结果与已有的电生理工作表明，听觉系统信息的加工与整合有系统外前脑边缘系统结构的参与。
The projections of the amygdala to the auditory cortex in rabbit were studied with both electrophysiological and retrograde axonal tracing techniques. The results of electrophysiological experiment showed that evoked potentials caused by amygdala stimulation spread widely in Woolsey′s AⅠ, AⅡ and the auditory cortex behind the rhinal sulcus (ACBRS), and the greatest potentials were recorded in ACBRS. The shortest latency of the evoked potential was only 2 ms, indicating that a direct projection from the amygdala to the auditory cortex did exist. Morphological research demonstrated that the greatest projection arises from the lateral amygdala, because the majority of retrogradely labeled cells were observed in the lateral amygdala and the minority in the basal part following ionophoretic injection of HRP into ACBRS, though both the lateral and basal nuclei contribute projections to the auditory cortex . In addition, the lateral nucleus sends a lighter projection to Woolsey′s AⅠ and AⅡ while the basal nucleus does not. Thus, our experiments suggest that the lateral nuclus is the major part projected to the auditory cortex and the ACBRS is the main area where the amygdaloid fibers project to. These results as well as the electrophysiological experiments indicate that the forebrain limbic structure out of the auditory system takes part in the processing and integration of the auditory information.
出处
《动物学报》
SCIE
CAS
CSCD
1998年第1期47-53,共7页
ACTA ZOOLOGICA SINICA
基金
国家自然科学基金
国家教委博士点基金
