摘要
研究AM治疗11例IgG亚类缺陷病患儿的疗效及机理。结果表明AM治疗使患儿缺陷的血清IgG1、IgG3水平升高,PBMC体外产生IFNγ水平升高。治疗半年后呼吸道感染频率及患病时间明显降低。提示AM部分改善IgG亚类缺陷患儿免疫功能。
bserved that the clinical effects of AM on 11 recurrent respiratory tract infection (RRTI) children with IgG subclass deficiency and its possible mechanism. The results showed that after treatment, serum IgG,IgG3 and IFNγ produced by PBMC from children with IgG subclass deficiency in vitro were increased. Followed up 6 months, the frequency of respiratory tract infection and the time remains of sickness days significantly decreased. It could imply that AM improves partial immunological capability of RRTI children resulting in remission of RRTI.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
1998年第4期283-284,共2页
Chinese Journal of Immunology
基金
国家自然科学基金
四川省卫生厅资助