摘要
为选择法乐四联症手术的适宜年龄，应用扫描电子显微镜对３０例法乐四联症病人的右室流出道心肌纤维进行观察，结果可见多数心肌纤维排列紊乱、增生、肥大；肌纤维表面横纹的宽度粗细不均，有的异常增宽、增高。细胞表面凹凸不平，在肌膜下可见异常大量堆积的线粒体。心肌纤维内的肌原纤维排列方向紊乱，致使横小管不在同一水平。心肌间质明显增生。随着年龄的增长，上述改变愈重。因此法乐四联症病人，在条件允许下。
Aim:To study the ultrastructural changes of myocardial fibres in Tetralogy of Fallot and its relationship to cardiac function.Clinical material and method:Thirty patients with Tetralogy of Fallot undergoing surgical correction were studyied.The myocardial tissues were taken from the right ventricule intraoperatively.Scanning electron microscopy was used for observing ultrastructural changes of the myocardial fibres.Results:Under scanning electron microscope the myocardial fibres showed disorderly arrangement,with loss of the normal parallel arrangement,variety degree of hyperplasia and hypertrophy.Numbers of midochondria were found under the sarcolemma.These ultrastructural changes were progressively with patients' age.Conclusion:Surgical repair for Tetralogy of Fallot should be performed as early as possible.
出处
《中华胸心血管外科杂志》
CSCD
北大核心
1998年第3期139-141,共3页
Chinese Journal of Thoracic and Cardiovascular Surgery
基金
卫生部基金资助(基金
关键词
法乐四联症
心肌纤维
扫描电镜
Tetralogy of Fallot Myocardial fibres Scanning electron microscopy
