视网膜神经节细胞分化发育影响因素的研究
摘要
视网膜细胞的产生有特定的高度保守的顺序,视网膜神经节细胞是最早产生的神经元,在视网膜内部和外部因素的共同作用下精确的发育分化,其调控因素主要有胞外因素(视网膜微环境中的可溶性因子)和胞内因素(视网膜细胞内在的各种调控基因)。本文主要对视网膜神经节细胞(Retinal ganglion cells,RGCs)发育分化影响因素的研究进展加以综述。
出处
《赣南医学院学报》
2009年第1期136-139,共4页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
参考文献35
-
1Kelley MW, Turner JK, Reh TA. Retinoic acid promotes differentiation of photoreceptors in vitro [ J ]. Development, 1994,120 ( 8 ) :2091 - 2102.
-
2Hyatt GA, Schmitt EA, Fadool JM, et al. Retinoic acid alters photoreceptor development in vivo [ J ]. Proc Natl Acad Sci USA, 1996,93 (23) : 13298 - 13303.
-
3Kelley MW, Turner JK, Reh TA. Ligands of steroid/thyroid receptors induce cone photoreceptors in vertebrate retina [ J ]. Development, 1995,121 ( 11 ) : 3777 - 3785.
-
4Levine EM, Roelink H, Tuner J, et al. Sonic hedgehog promotes rod photoreceptors differentiation in mammalian retinal cells in vitro [ J ]. J Neurosci, 1997, 17 ( 16 ) : 6277 - 6288.
-
5Fuhrmann S, Heller S, Rohrer H, et al. A transient role for ciliary neurotrophic factor in chick photoreceptor development[ J]. J Neurosci, 1998,37 (4) :72 - 83.
-
6Kirsch M, Culz KS, Wiese A, et al. Ciliary neurotrophic factor blocks rod photoreceptor differentiation from post- mitotic presuror cell in vitro[J]. Cell Tissue Res, 1998, 291(2) :207 -216.
-
7Yoarey PA, Gohari S, Su JL, et al. Vascular endothelial cell growth factors promote the in intro development of rat photoreceptor cells[ J]. J Neurosci, 2000,20(18) :6781 - 6788.
-
8Yang K, Cepko CL, Flk-1. a receptor for vascular endothelial growth factor( VEGF), is expressed by retinal progenitor cells [ J ]. J Neurosei, 1996,16 ( 19 ) : 6089 - 6099.
-
9Uteza Y, Rouillot JS, Kobetz A, et al. Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2 delays photoreceptor cell degeneration in Royal Collage of Surgeons rats [ J ]. Proc Natl Acad Sci USA, 1999,96(6) :3126 -3131.
-
10Davis AA, Matzuk MM, Reh TA. Activin A promotes progenitor differentiation into photoreceptors in rodent retina[J]. Mol Cell Neurosci, 2000, 15(1) :11 -21.
二级参考文献15
-
1刘卫平,潘灏,章翔,姬西团,王彦刚,王西玲,梁景文.神经干细胞原代培养及GABA能神经元的诱导分化[J].中华神经外科疾病研究杂志,2005,4(1):44-47. 被引量:14
-
2Bertrand N,Castro DS,Guillemot F.Proneural genes and the specification of neural cell types[J].Nat Rev Neurosci,2002,3(7):517-530.
-
3Ross SE,Greenberg ME,Stiles CD.Basic helix-loop-helix factors in conical development[J].Neuron,2003,39(1):13-25.
-
4Yamamoto N,Yamamoto S,Inagaki F,et al.Role of Deltex-1 as a transcriptional regulator downstream the Notch receptor[J].J Biol Chem,2001,276(48):45031-45040.
-
5Mizuguchi R,Sugimori M,Takebayashi H,et al.Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of panneuronaland subtype-specific properties of motoneurons[J].Neuron,2001,5(5):757-771.
-
6Vetter M.A turn of the helix:preventing the glial fate[J].Neuron,2001,29(3):559-562.
-
7Nieto M,Sehuurmans C,Britz O,et al.Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors[J].Neurol,2001,29(2):401-413.
-
8Lee SK,Pfaff SL.Transcriptional networks regulating neuronal identity in the developing spinal cord[J].Nat Neurosci,2001,4(Suppl):1183-1191.
-
9Cai L,Morrow EM,Cepko CL.Misexpression of basic helix-loop-helix genes in the mufine cerebral cortex affect cell fate choices and neuronal survival[J].Development,2000,127(13):2933-2943.
-
10Bae S,Bessho Y,Sojo M,et al.The bHLH gene Hes6,an inhibitor of Hes1,promotes neuronal differentiation[J].Development,2000,127(13):2933-2943.
-
1姚静,孙兴怀.Math5对视网膜神经节细胞的分化调控[J].国际眼科纵览,2006,30(1):35-39. 被引量:1
-
2谢青松,李立新,陶轶,胡卫星,黄保胜.脑源性神经营养因子促进bHLH基因的表达和神经干细胞的定向分化[J].中国神经精神疾病杂志,2006,32(6):540-542. 被引量:11
-
3龙乾发,刘卫平.bHLH和Hox基因对GABA能神经元诱导分化研究进展[J].中华神经外科疾病研究杂志,2010,9(6):564-566. 被引量:2
-
4徐琦,丁剑冰,马秀敏,薛志琴.不同细胞因子诱导的小鼠骨髓树突状细胞亚群与小鼠脾脏树突状细胞亚群的比较[J].免疫学杂志,2010,26(8):661-664. 被引量:2
-
5安小惠,蔡国平.人脐带血中粘附前体细胞的研究[J].中国病理生理杂志,2003,19(11):1449-1452.
-
6李依孺,叶茂,吴楠,王一.视网膜干细胞体外诱导分化为神经节细胞的初步研究[J].第三军医大学学报,2014,36(10):1026-1030.
-
7李博,王春凤,杨桂连.自然杀伤细胞在机体免疫中的作用及机制研究进展[J].中国免疫学杂志,2015,31(5):719-720. 被引量:13
-
8万东君,王春雨,李六金.肝干细胞研究现状[J].世界华人消化杂志,2002,10(4):452-454. 被引量:7
-
9张勇,朱春然,陶轶.脑源性神经营养因子对胎鼠神经干细胞向神经元方向分化的诱导[J].中国组织工程研究与临床康复,2008,12(51):10073-10076. 被引量:5
-
10苏中静,黄东阳,陈海滨.fascin在树突细胞分化发育和抗原呈递中的作用[J].中华血液学杂志,2008,29(6):423-425.