摘要
目的探讨门静脉切除重建联合胰十二指肠切除术治疗胰头癌的临床意义。方法回顾性分析21例行联合门静脉（PV）和／或肠系膜上静脉（SMV）、胰十二指肠切除术患者的临床资料，分析手术并发症及其预后。结果全组围手术期并发症发生率为19．04％（4／21），其中2例胃潴留，1例上消化道出血，1例切151裂开，无胆胰瘘并发症。围手术期（术后1个月内）病死率4．76％（1／21）。20例患者生存期为6—67个月，平均（20．38±9．36）个月。患者术后1，3，5年生存率分别是65．9％，16．0％和10．2％。结论有选择的施行血管切除有助于提高局部较晚期胰头癌的切除率，能明显改善患者的生存质量，在一定程度上延长了生存期。
Objective To study the value of pancreaticoduodenectomy in combination with portal vein （PV） resection and reconstruction in the treatment of pancreatic carcinoma. Methods The clinical data of 21 patients who received panereatieoduodeneetomy in combination with PV resection and reconstruction in the treatment of pancreatic carcinoma in our hospital in the past 6 years were retrospectively analyzed. Results Perioperative complication incidence was 19.04% （4/21） and mortality rate was 4.76% （1/21）. The major complications included delayed gastric emptying （9.52%） , gastrointestinal bleeding （4.76%） and disruption of wound （4.76%）, but no pancreatic leakage was observed. The survival time of 20 subjects ranged from 6 to 67 months [ mean （20.38 -＋9.36） month], The survival rate at ly, 3y and 5y of the 21 subjects in this study were respectively 65.9 % , 16.0 % , 10.2 %. Conclusions Conduction of en bloc resection with the invaded PV/ SMV is safe and feasible for patients with locally advanced pancreatic adenocareinoma. Major vascular resection can increase the resection rate, improve life quality and extend patient survival time.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2009年第3期264-267,共4页
China Journal of General Surgery
关键词
胰腺肿瘤/外科学
胰十二指肠切除术
肿瘤侵犯
血管重建
Pancreatic Neoplasms/surg
Pancreaticoduodenectomy
Neoplasm Invasiveness
Revascularization
