摘要
目的探讨超声检查判断胰腺癌周围血管侵犯情况及其可切除性的价值。方法回顾性分析2012年1月至2017年9月中山大学附属第三医院收治的33例胰腺癌患者临床资料。患者均签署知情同意书,符合医学伦理学规定。其中男21例,女12例;年龄46～75岁,中位年龄54岁。术前行超声检查评估胰腺癌对周围血管侵犯情况,评估肿块可切除性,并与术中探查结果及实际手术对比,计算其敏感性和特异性。结果超声评价胰腺癌侵犯胰周血管的敏感性为88%(30/34),特异性99%(261/263),阳性预测值94%(30/32),阴性预测值98%(261/265)。对19例有血管侵犯但无远处转移及淋巴结转移者,超声判断其不可切除的敏感性为5/6,特异性12/13,阳性预测值5/6,阴性预测值12/13。结论超声检查可较准确可靠地判断胰腺癌对周围血管的侵犯情况,对可切除性的评估有一定参考价值。
Objective To investigate the diagnostic value of ultrasonography in the assessment of peri-pancreatic vascular invasion and resectability of pancreatic cancer. Methods Clinical data of 33 patients with pancreatic cancer admitted to the Third Affiliated Hospital of Sun Yat-sen University from January 2012 to September 2017 were retrospectively analyzed. The informed consents of all patients were obtained and the local ethical committee approval was received. Among them, 21 patients were male and 12 were female, aged 46-75 years with a median age of 54 years. Peri-pancreatic vascular invasion was evaluated by preoperative ultrasonography and the resectability of tumors was assessed. The ultrasonography findings were compared with the intraoperative exploration and surgical outcomes. And its sensitivity and specificity were calculated. Results The sensitivity, specificity, positive and negative predictive rates of ultrasonography in evaluating the peri-pancreatic vascular invasion were 88% （30/34） , 99% （261/263） , 94% （30/32） and 98% （261/265） , respectively. For 19 patients with vascular invasion but without distant metastasis or lymph node metastasis, the sensitivity, specificity, positive and negative predictive rates of ultrasonography in assessing the unresectability were 5/6, 12/13, 5/6 and 12/13, respectively. Conclusions Ultrasonography can accurately and reliably evaluate the peri-pancreatic vascular invasion and give reference for assessing the resectability of pancreatic cancer.
作者
刘佳
傅斌生
郑荣琴
尹庭辉
李凯
Liu Jia, Fu Binsheng, Zheng Rongqin, Yin Tinghui, Li Kai.(Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China)
出处
《中华肝脏外科手术学电子杂志》
CAS
2018年第5期410-413,共4页
Chinese Journal of Hepatic Surgery(Electronic Edition)
基金
广东省科技计划项目(2017A020215137)
关键词
超声检查
胰腺肿瘤
肿瘤侵润
诊断
Ultrasonography
Pancreatic neoplasms
Neoplasm invasiveness
Diagnosis
