摘要
糖尿病视网膜病变（DR）是糖尿病常见并发症，具有高发病率、高致盲率。DR的发生可能与多元醇通路激活、细胞因子、蛋白质的非酶糖基化、糖化血红蛋白（GHb）、高血糖记忆及易感基因等有关。眼底荧光血管造影（FFA）、视觉诱发电位是诊断DR的新的手段。非增生期DR的治疗主要包括血糖、血脂及血压控制，糖基化终产物（AGE）抑制剂、蛋白激酶C抑制剂和如血管内皮生长因子（VEGF）抑制剂治疗。当DR进入增生前期及增生期时，视网膜光凝和玻璃体手术成为主要治疗手段。新的药物为中晚期DR治疗提供了帮助。
Diabetic retinopathy is a common complication of diabites, it is related to various factors, such as abnormal matabolism of polyalcohol, cytokine, glycosylation of protein, glycosylated hemoglobin, hyperglycaemia memory and predisposing genes. Fluorescence fundus angiography （FFA） and Vision-evoked potential are new methods in the diagnosis of diabetc retinopathy. Photo-coagulation and Operation on vitreous beccomes major therapeutic tool to diabetc retinopathy. New drugs are helpful to advanced stage of diabetc retinopathy.
出处
《医学综述》
2009年第6期898-900,共3页
Medical Recapitulate
关键词
糖尿病视网膜病变
发病机制
诊断
治疗
Diabitic retinopathy
Pathologic mechanism
Diagnosis
Treatment
