摘要
目的:观察华蟾素注射液联合希罗达治疗晚期消化道恶性肿瘤的疗效。方法:将患者随机分为两组,治疗组30例采用华蟾素注射液20ml+5%葡萄糖500ml,静滴,每日1次,连用15天;希罗达1g-1.5g,每日两次,口服,连用14天。对照组30例用希罗达1g-1.5g,1日两次,口服,连用14天。21天为1周期,共用2周期。结果:治疗组有效率为53.3%,疼痛缓解率为63.3%;对照组有效率46.7%,疼痛缓解率为56.7%;两组相比治疗组优于对照组,但差异未达显著性(P>0.05)。治疗组生活质量改善率为73.3%,白细胞下降率为16.8%;对照组生活质量改善率为26.7%,白细胞下降率为46.7%;两组相比均有显著差异(P<0.05)。结论:华蟾素注射液配合希罗达治疗晚期消化道恶性肿瘤能明显缓解症状,改善生活质量,疗效确切。
Objective：To study the effect of cinobufacini toad-injection with xeloda for advanced gastrointestinal cancer.Methods： Sixty patients were randomly divided into two groups treatment group（30 cases）using cinobufacini injection 20ml ＋5% glucose infusion 500 ml ivgtt,once a day,for 15 days,xeloda 1g-1.5g,twice daily,for 14 days.The control group（30 cases） treated with xeloda 1g-1.5g,for 14 days.Results： Effective rate in the treatment group was 53.3%,pain remission rate 63.3%;effective rate in the control group was 46.7%,pain remission rate 56.7%（P〉 0.05）.The rate of improving the quality of life in the treatment group was 73.3%,drop of white blood 16.8%;but for control group was 26.7% and 46.7%（P〈0.05）.Conclusion： Cinobufacini injection with xeloda for advanced gastrointestinal cancer can significantly improve the symptoms,and quality of life of the patients.
出处
《现代肿瘤医学》
CAS
2009年第3期498-499,共2页
Journal of Modern Oncology
关键词
华蟾素注射液
消化道恶性肿瘤
化疗
希罗达
cinobufacini injection
gastrointestinal cancer
chemotherapy
xeloda
