摘要
目的记录几种黄斑病变的局部视网膜电图（ｌｏｃａｌｅｌｅｃｔｒｏｒｅｔｉｎｏｇｒａｍ，ＬＥＲＧ），确定其在黄斑病变诊断中的应用价值。方法采用局部光刺激器，对五种类型黄斑病变患者进行黄斑区２．５°、５．０°、７．５°三个范围的ＬＥＲＧ测定。结果（１）在所观察的黄斑病变中，Ｓｔａｒｇａｒｄｔ病、湿性老年黄斑变性、黄斑裂孔及中心性浆液性脉络膜视网膜病变的ＬＥＲＧ振幅较正常对照组降低，差异有显著性（Ｐ＜０．０１），且异常率较高；干性老年黄斑变性及黄斑部视网膜前膜的ＬＥＲＧ振幅则无显著改变。（２）ＬＥＲＧ异常率也与刺激范围有关。在所观察记录的三个范围中，以２．５°的ＬＥＲＧ异常率最高。结论不同类型黄斑病变对黄斑区视网膜电活动的影响程度存在总体差异。ＬＥＲＧ是测量黄斑功能的一种有效的电生理方法。
Objectives To record the local electroretinogram (LERG) in macular diseases, and define the using value of LERG in macular diseases. Methods The LERGs of five kinds of maculopathies were recorded with a spot light stimulator at 2.5, 5 0, 7.5 degrees of macular region. Results (1) The amplitudes of LERG at the three regions in Stargardt's disease, wet form age related macular degeneration (AMD), central serous chorioretinopathy, and idiopathic macular hole were significantly lowered in comparison with the controls ( P <0.01). In the meanwhile, these diseases also showed high abnormal rates. While in dry form AMD and epiretinal membrane, the amplitudes of LERG had no significant changes ( P >0.05). (2) The abnormal rates of LERG were related to the stimulated area. In the three tested areas, the highest abnormal rates occurred at 2.5 degrees. Conclusions There are mean differences in macular electrical activities in these maculopathies. LERG is an effective method of electrophyisology for testing macular function.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
1998年第1期42-44,共3页
Chinese Journal of Ophthalmology
关键词
黄斑变性
视网膜电图
Macular disease Electroretinogram
