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应用自体静脉做动脉重建时血管内皮细胞早期动态变化的研究

A endothelial coverage in the autogenous vein graft for arterial reconstruction in the early stage
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摘要 目的观察用自体静脉(AVG)移植做动脉重建后,前列腺素1对血管内皮细胞(EC)早期变化的影响。方法40只犬被分成两大组,根据重建动脉远端输出道良否,扩血管药物前列腺素1(PGE1)投入与否再分成八小组。移植后AVG标本通过处理,用图像分析系统,测定EC的脱落与覆盖面积。结果(1)被建动脉良好的输出道对移植后AVG内EC再生与修复有明显促进作用,PGE1的投入无此作用。(2)AVG内瓣膜部位是移植后EC再生与修复的发源地。结论做血管移植时应尽量保护AVG内瓣膜。 Objective To sequentially study the endothelial cell(EC)in the autogenous vein graft(AVG)for arterial construction in the early stage.Methods Forty dogs were divided in to two groups.After the artery reconstructed and intravenous injection or nonintravenous injection of PGE 1,the dogs were divided in to groups.The deendothelialization and reendothelialization of AVG were determined by the portrayal apparatus.Results Excellent results in renovation of EC to the AVG were observed after establish ment of runing off of was reconstructed artery without intravenous injection of PGE1.The valve of AVG is very important inrenovation of EC.Conclusion It must be protected when artery is reconstructed by AVG.
出处 《中华外科杂志》 CAS CSCD 北大核心 1998年第1期29-30,共2页 Chinese Journal of Surgery
关键词 内皮细胞 血管 血管移植 静脉移植 动脉重建 Graft occlusion,vascular Veins Turica intima
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