摘要
目的：研究国产Ｎｄ：ＹＡＧ激光经皮腔内协助球囊血管成形术（ＰＴＬＢＡ）治疗髂、股动脉闭塞性硬化疾病的临床应用价值。材料和方法：对１３例髂动脉、股动脉闭塞性硬化患者的１５段闭塞血管用激光行ＰＴＬＡ再通后，再用球囊导管行ＰＴＡ扩大血管管腔，并局部灌注４－１０万尿激酶，术后抗凝、溶栓治疗一月左右。结果：当时血管造影显示闭塞血管再通率达８０％，平均踝一臂压力指数从０４５±０２０升至０８０±０１６（Ｐ＜０００１），１例发生血管穿孔，在６－１５个月（平均１１±５月）随访期内，１２例临床症状持续缓解，１例症状加重，踝一臂压力指数下降。结论：ＰＴＬＢＡ对髂、股动脉闭塞性硬化的治疗是安全有效的，作者对ＰＴＬＢＡ的作用机理和并发症进行了讨论。
urpose: To evaluate laserassisted balloon angioplasty(LABA) with domesticmade Nd:YAG laser in the treatment of iliacfemoral atherosclerotic occlusion.Materials and Methods: After laser recanalization of 15 iliacfemoral arterial occlusions in 13 atherosclerotic patients,balloon catheter was then used to widen the lumen furthermore simultaneously with local infusion of 4×104～10×104μ of urodinase. All patients received anticoagulative and thrombolytic therapy for about 1 month. Results: Immediate angiography showed that initial clinical success was achieved in 12(80%) of 15 segments and increase in mean anklebrachial pressure ratio from 045±020 to 080±016(P<0001).vascular perforation occured only in 1 case. During 6 to 15 months’(mean 11±5 months) followup,clinical symptomatic relief still existed in 12 cases,symptomatic worse and decrease of anklebrachial index were found only in 1 case. Conclusion: LABA with the Nd:YAG laser appears to be a safe and useful method in the recanalization of iliacfemoral atherosclerotic occlusions. Authors have discussed the mechanism and complications of LABA.
出处
《中国医学计算机成像杂志》
CSCD
1998年第1期49-52,共4页
Chinese Computed Medical Imaging
