摘要
利用MALDI-TOFMS测定了八种人参皂苷的分子量,并分析了西洋参总皂苷的组成.同时,进行了灵敏度实验,并探讨了基质及碱金属离子的影响,证明该方法灵敏度高,重复性好,结果准确.是测定极性小分子分子量的有效方法.
Molecular weight of 8 ginsenosides and the component of total saponions in American ginseng have been determined by matrix - assisted laser desorption/ionization mass spectrometry (MALDI - MS). The average error of the molecular weight of each ginsenoside was found less than 0.05 %. The results demonstrate that MALDI-MS is a very simple and useful method to measure the molecular weight of some high polar, thermal unstable small molecules with high sensitivity and reproducibility.
出处
《化学学报》
SCIE
CAS
CSCD
北大核心
1998年第3期298-301,共4页
Acta Chimica Sinica
关键词
质谱
人参皂苷
分子量
MALDI
西洋参
皂苷
Matrix - assisted laser desorption/ionization mass spectrometry, ginsenosides, molecular weight
