摘要
目的观察胰岛素泵和传统胰岛素皮下注射2种方法对2型糖尿病患者短期强化治疗中的血糖控制及胰岛素用量情况。方法32例2型糖尿病患者随机分成胰岛素泵(CSII)组和多次胰岛素注射(MDII)组,比较2组治疗前后空腹及餐后2h血糖、胰岛素用量、血糖达标时间及低血糖反应。结果CSII组和MDII组空腹及餐后2h血糖逐渐降低(P>0.05),但CSII组胰岛素用量少,达标时间短,且低血糖发生率低(P<0.01)。结论胰岛素泵是2型糖尿病短期强化控制血糖的安全有效、简便可靠的手段。
Objective To compare the efficacy continuous subcutaneous infusion of insulin （CSII） versus multiple daily insulin injection （MDII） in patients with type 2 diabetes by assessing 32 fasting blood glucose and daily insulin dosage. Methods Hospitalized type 2 diabetic patients were randomly assigned to CSII and MDII. FBG and 2 hours post - meal BG were performed. The treatment days when blood glucose was well controlled and the insulin dosage at that time were observed. Results The values of BG and 2 hours post - meal BG decreased gradually, and no significant difference was found between group CSII and MDII （ P 〉 0.05 ）. But the insulin doses necessary to maintain adequate blood glucose in group CSII were less than in group MDII, with a shorter treatment time and lower hypoglycaemia incidence rate （P 〈 0. 01 ）. Conclusion CSII and MDII were comparable in rapidly improving hyper glYcaemia in uncontrolled type 2 diabetic patients CSII, being more safe and convenient, could be preferred as a short- term intensive insulin therapy.
出处
《临床合理用药杂志》
2009年第1期8-9,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
2型糖尿病
胰岛素泵
血糖
Type 2 diabetes
Continuous ubcutaneous infusion of insulin
Blood glucose
