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急性非淋巴细胞白血病预后相关因素(附62例分析)

Analysis of prognostic associated factors in 62 cases of acute nonlymphocytic leukemia
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摘要 目的:为探索影响预后的因素,对62例急性非淋巴细胞白血病住院患者进行了回顾分析。方法:单变量和多变量分析24项影响完全缓解的变量及31项影响生存期的变量。结果:表明仅就诊时脾无肿大和骨髓涂片巨核细胞数目≤1个/1.5×2cm2对CR有利。对CR患者仅第一次缓解期、脾脏有无肿大、治疗前白细胞数值及有无复发对生存时间有显著影响。结论:以上结果的CR和生存期判断提供了具有参考意义的相关因素,值得临床上进一步扩大验证。 Objectives: To explore the influence factors upon prognosis,we made retrospective analysis in 62 cases of acute nonlymphocytic leukemia. Methods:Twenty four variances influencing complete remission(CR) and 31 variances influencing survival were analysed to employ analytic method of uni and multivariaces. Results: Only no splenomegaly and number of megakaryocyte ≤1/1.5×2 cm2 on bone marrow smear were favorable to CR.For CR's patients.The results suggested only first remission duration, splenomegaly, WBC count before therapy and relapse to show significantly influence to survival. Conclusions: Above results provided associated factors that judged CR and survival to possess refering value,it deserved climical continued study to confirm these results in large series in the future.
作者 马昊 王学文
出处 《南京大学学报(自然科学版)》 CAS CSCD 1998年第2期234-238,共5页 Journal of Nanjing University(Natural Science)
关键词 白血病 预后因素 ANLL 急性白血病 Acute nonlymphocytic leukemia Prognotic factor
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  • 1仇红霞,临床内科杂志,1992年,9卷,14页
  • 2林果为,白血病,1989年

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