摘要
学习近年来海绵体神经损伤后神经重建的方法,查阅与海绵体神经重建修复、勃起功能恢复和神经重建组织学工程相关的文献,发现多种不同材料的移植物用于海绵体神经修复,包括自体神经移植、硅胶管及人工合成的可降解的生物材料。神经营养因子、神经细胞外基质和雪旺氏细胞有助于促进神经的修复。人工合成的神经再生支架材料,尤其是含有神经营养因子和活性细胞的可降解生物材料,是一种比较有前途的海绵体神经修复的治疗方案。
By studying the novel methods for reconstructing damaged cavernous nerves and the related literature on the regeneration of cavernous nerves, restoration of erectile function and neurohistological reconstruction engineering, a variety of grafting materials have been found applicable to cavernous nerve reconstruction, including autogenetic nerve grafts, silicone tubes, artificial biodegradable conduits and so on. Neurotrophic factors, extra cellular matrix components and Sehwann cells have been shown to promote cavernous regeneration. Artificial nerve guides, especially biodegradable ones containing growth-promoting factors or cells, are a promising option for the repair of cavernous nerve lesions.
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2009年第1期65-68,共4页
National Journal of Andrology
