摘要
目的：探讨β2─糖蛋白Ⅰ（β2─GPI）在体内的分布。方法：以昆明系小鼠为实验模型，将纯化的小鼠β2─GPI用Na125I标记，注入到小鼠体内，80min后取一些重要脏器做放射性计数测定。结果：Na125I─β2─GPI放射性计数在血浆中为215．01±16．45Bq·g-1，在肾脏中为51．57±6．30Bq·g-1，在肝脏中为49．38±5.14Bq·g-1,在肺中为11.96±1.52Bq·g-1。结论：在所取的各组织脏器中，血浆中分布最多，肾、肝次之，在肺中分布最少。
Objective:Kunwing mice were made to be the test model in order to study the distribution of β2 -GP I. Methods:First,isolated β2-GP I was labeled by Na125I,and then injected into the mouse fortes. Some of the organs were taken out and Bq value was measured after 80 min. Results: radioactive value was 215.01±16. 45 Bq·g-1 in plasma, in kidney it was 51. 57±6. 30Bq·g-1,in liver it was 49. 38±5. 14 Bq·g-1 and in lung it was 11. 96±1. 52Bq·g-1. Conclusion: The results may suggest that the distribution of Na125I-β2-GP I in plasma was the most,and next in kidney and in liver. The least was in lung.
出处
《白求恩医科大学学报》
CSCD
1998年第2期122-123,共2页
Journal of Norman Bethune University of Medical Science
基金
国家自然科学基金!39570317
