摘要
本实验用健康雄性家兔１５只，以直接撞击法造成左胫骨中段闭合性骨折，并将动物随机均分为三组：实验组外敷消瘀接骨散；药物对照组外敷七厘散；空白对照组不用任何药物。骨折后１、２、３、４周，分别经耳缘静脉或股外侧静脉抽血，行血碱性磷酸酶（ＡＫＰ）活性及血钙、磷含量检查，观察消瘀接骨散对骨折愈合的影响。实验结果显示：消瘀接骨散能够增加血ＡＫＰ活性、降低血钙、升高血磷和钙磷乘积，从而说明消瘀接骨散具有促进骨折愈合的作用，而且作用强于七厘散。
For investigating the effect of Xiao Yu Jie Gu San on healing of fracture, experimental closed fractures were made at the middle segments of left tibias in 15 healthy male rabbits with direct stroke. The animals were randomly and equally divided into three groups: experimental group treated externally with Xiao Yu Jie Gu San, medicinal control group treated externally with Qi Li San, and bland control group without any drugs. At the first, second, third and forth weeks after fracture, blood was drawn from the marginal vein of auricle or from the lateral vein of knee, and the activity of alkaline phosphatase (AKP) and the content of calcium and phosphorus in blood were examined. The results showed that Xiao Yu Jie Gu San can increase the activity of AKP, decrease the content of blood calcium, and increase the content of blood phosphorus and the product of calcium and phosphorus. Thus it demonstrated that Xiao Yu Jie Gu San plays a role in promoting the healing of fracture and its effect is better than that of Qi Li San.
出处
《中国骨伤》
CAS
1998年第1期19-21,共3页
China Journal of Orthopaedics and Traumatology
